Tradjenta Side Effects
A sore throat and a runny or stuffy nose are the most common side effects reported with Tradjenta. Other possible problems may include coughing and weight gain. Although most side effects do not require medical attention, you should notify your healthcare provider right away if you experience confusion, seizures, difficulty breathing, or other potentially serious reactions.
Just like any medicine, Tradjenta™ (linagliptin) can cause side effects. However, not everyone who uses the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Tradjenta. Your healthcare provider can discuss a more complete list with you.)
Tradjenta has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking Tradjenta were documented and then compared to the side effects that occurred in a similar group of people taking a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it is possible to see what side effects occurred, how often they appeared, and how they compared to the group taking the placebo.
In some of the studies, Tradjenta (or the placebo) was used alone; in other studies, Tradjenta (or the placebo) was combined with other diabetes medications.
In these studies, the most commonly reported Tradjenta side effects included:
- Nasopharyngitis (a term for common cold-like symptoms, such as a runny or stuffy nose or a sore throat) -- in up to 4.3 percent of people
- High cholesterol -- up to 2.7 percent
- Coughing -- up to 2.4 percent
- High triglycerides -- up to 2.4 percent
- Weight gain -- up to 2.3 percent.
These statistics may be slightly misleading. When looking at the "big picture" of the various studies with this medication, none of these side effects seem to be strongly linked with Tradjenta. For instance, weight gain was seen in only one study in which Tradjenta was combined with pioglitazone (Actos®); it was not seen in any of the other studies in which Tradjenta was used alone or combined with any other diabetes medications.