If Tradjenta (linagliptin) is not adequately treating your type 2 diabetes or is causing bothersome side effects, there are several alternatives to consider. Some of these alternatives can include lifestyle changes and other diabetes medications. Because there is no single diabetes treatment that works for everyone, make sure to talk to your healthcare provider about which option is best for your situation.
An Overview of Alternatives to Tradjenta
Tradjenta® (linagliptin) is a prescription medication used for the treatment of type 2 diabetes. It is part of a group of diabetes medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. For most people, Tradjenta is an effective diabetes medicine that is generally well tolerated. However, as with all medicines, side effects can occur. In addition, the medicine may not completely control a person's diabetes in some cases.
Fortunately, there are several alternatives to Tradjenta for type 2 diabetes. Some of these alternatives include:
Oral Diabetes MedicinesFortunately, there are many other different types of oral diabetes drugs available to treat type 2 diabetes, including:
- Other dipeptidyl peptidase inhibitors
- Alpha glucosidase inhibitors
- Ergot alkaloids
- Sodium-glucose co-transporter 2 inhibitors (SGLT2 inhibitors)
- Bile acid sequestrants
- Combination medications.
Other Dipeptidyl Peptidase Inhibitors
Tradjenta is part of a class of diabetes drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. DPP-4 is an enzyme that breaks down incretin hormones. As a DPP-4 inhibitor, Tradjenta slows down the breakdown of incretin hormones, increasing the level of these hormones in the body. It is this increase in incretin hormones that is responsible for the beneficial actions of Tradjenta, such as increasing insulin production in response to meals and decreasing the amount of glucose (sugar) that the liver produces.
There are three other medications closely related to Tradjenta. These medications are sitagliptin (Januvia®), saxagliptin (Onglyza®), and alogliptin (Nesina®). All of these drugs can be used in combination with many other diabetes medications and are all relatively unlikely to cause dangerously low blood sugar levels.