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Precautions and Warnings With Sitagliptin/Simvastatin

People who are taking sitagliptin/simvastatin should know that this medication may increase the risk for a potentially serious breakdown in the muscles of the body that can lead to kidney failure. Also, this medicine should not be used by people who have active liver disease or those taking certain medications. Other warnings and precautions with sitagliptin/simvastatin apply to women who are pregnant or breastfeeding.

In September 2013, Merck & Co, Inc., announced that it would be discontinuing this medication. It is clear that this decision was made for business reasons, not for safety reasons.
 

What Should I Tell My Healthcare Provider Before Taking Sitagliptin/Simvastatin?

You should talk with your healthcare provider prior to taking sitagliptin/simvastatin (Juvisync®) if you have:
 
  • A history of pancreatitis
  • Liver disease, liver failure, or a history of liver disease
  • Kidney disease or kidney failure
  • Hypothyroidism
  • Any allergies, including to foods, dyes, or preservatives.
 
Let your healthcare provider know if you are:
 
  • Pregnant or thinking about becoming pregnant
  • Breastfeeding.
 
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 
Also, make sure to contact your healthcare provider immediately if you experience any muscle pain, weakness, or tenderness, especially if it is accompanied by body aches or a fever.
 
Healthy Eating for People With Diabetes

Sitagliptin/Simvastatin Drug Information

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