Sitagliptin and Metformin (Cont.)

Effects of Sitagliptin and Metformin

Hemoglobin A1c (HbA1c) is a test used to measure long-term blood sugar control. For people without diabetes, HbA1c results are usually less than 6 percent, while people with diabetes usually have higher results. In one study, people taking the combination drug lowered their HbA1c by 0.7 percent more than people taking metformin alone.
 
Studies have shown that the higher the HbA1c, the greater the chance for developing long-term problems related to diabetes. This includes such problems as:
 
 
By getting blood sugar levels under control with sitagliptin and metformin, it may be possible to decrease the chances of developing these diabetes-related complications.
 

When and How to Take Sitagliptin and Metformin

General considerations for when and how to take sitagliptin and metformin include the following:
 
  • The medication comes in tablet form. It should be taken by mouth twice daily.
     
  • Sitagliptin and metformin should be taken with food.
     
  • The medication should be taken at the same time(s) each day to maintain an even level in your blood.
     
  • For sitagliptin and metformin to work properly, it must be taken as prescribed. The drug will not work if you stop taking it.
     

Dosage Information for Sitagliptin and Metformin

The dose of sitagliptin and metformin that your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • How well your diabetes is controlled
  • Other medical conditions you may have
  • Other medications you may currently be taking.
     
As is always the case, do not adjust your sitagliptin and metformin dose unless your healthcare provider specifically instructs you to do so.
 
(Click Sitagliptin and Metformin Dosing for more information.)
 
(Sitagliptin and Metformin Continued: Page 3)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;