Side Effects of Sitagliptin and Metformin

Possible side effects of sitagliptin and metformin include nausea or vomiting, abdominal pain, and diarrhea. In most cases, these side effects are minor and don't require medical attention. Some sitagliptin and metformin side effects, however, should be reported to your healthcare provider right away, including symptoms of high or low blood sugar and signs of an allergic reaction.

 

Side Effects of Sitagliptin and Metformin: An Introduction

As with any medicine, side effects are possible with sitagliptin and metformin (Janumet®); however, not everyone who takes the medication will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can be easily treated by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with sitagliptin and metformin. Your healthcare provider can discuss a more complete list of sitagliptin and metformin side effects with you.)
 

Common Side Effects of Sitagliptin and Metformin

Sitagliptin and metformin has been studied thoroughly in clinical trials, in which a group of people taking the drug have side effects documented and compared to another group not taking the medicine.
 This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
 
In these studies, the most common sitagliptin and metformin side effects included:
 
  • Diarrhea -- in up to 2.4 percent of people
  • Abdominal pain (stomach pain) -- up to 2.2 percent
  • Nausea -- up to 1.3 percent
  • Vomiting -- up to 1.1 percent
     
(Side Effects of Sitagliptin and Metformin Continued: Page 2)
Add this article to your Favorites     Email this article     Print
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;