Precose Drug Interactions

Taking Precose along with calcium channel blockers, corticosteroids, or diuretics (among other medications) can make Precose less effective, increasing your risk of high blood sugar. Precose can also interact with some medicines -- including sulfonylureas and insulin -- to increase your risk of low blood sugar. You should make sure to talk with your pharmacist or healthcare provider about any Precose drug interactions that may apply to you.

An Overview of Precose Drug Interactions

 Precose® (acarbose) can potentially interact with a number of other medicines. Some of the medicines that may lead to Precose interactions include:
 
o Betamethasone (Celestone®)
o Cortisone
o Dexamethasone (Decadron®)
o Fludrocortisone (Florinef®)
o Hydrocortisone (Cortef®)
o Methylprednisolone (Depo-Medrol®, Medrol®)
o Prednisolone (Ovapred®, Pediapred®)
o Triamcinolone (Kenalog®, Aristospan®)
  • Digestive enzyme replacements, such as amylase, pancreatin, and pancrelipase
     
  • Diuretics, such as:
o Acetazolamide (Diamox®)
o Chlorthalodone
o Chlorpropamide (Diabinese®)
o Glipizide (Glucotrol®, Glucotrol XL®, Metaglip®)
o Tolazamide (Tolinase®)
o Tolbutamide (Orinase®)

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(Precose Drug Interactions Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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