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Clinical Studies

Hemoglobin A1c (HbA1c) is a test used to measure long-term blood sugar control. In one study, people who switched from metformin to PrandiMet lowered their HbA1c by up to 1.4 percent on average. In the same study, people taking metformin or repaglinide alone did not lower their HbA1c as much as people taking PrandiMet.
Fasting blood sugar is another way to study the effects of diabetes drugs. In studies, people who switched from metformin to PrandiMet decreased their fasting blood sugar levels by 39 mg/dL on average, while people taking metformin or repaglinide alone had only small decreases (or even increases) in fasting blood sugar, on average.

When and How to Take PrandiMet

Some general considerations include the following:
  • PrandiMet comes in tablet form. It is usually taken by mouth two or three times a day before meals.
  • It is best to take this medication 15 minutes before a meal, although you can take it up to 30 minutes before a meal if necessary. If you skip the meal, you should also skip your dose.
  • For the medication to work properly, it must be taken as prescribed. It will not work if you stop taking it.

Dosing Information

The dose of PrandiMet that your healthcare provider recommends will vary, depending on a number of factors, including:
  • How well your diabetes is controlled
  • Other medications you are taking
  • Any other medical conditions you may have.
As is the case with any medicine, do not adjust your PrandiMet dose unless your healthcare provider specifically instructs you to do so.
(Click PrandiMet Dosage for more information.)
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