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PrandiMet Interactions

Make sure to talk to your healthcare provider about any other medications you are taking before starting treatment with PrandiMet. Drug interactions could occur if PrandiMet is taken with certain medications, such as some antibiotics, protease inhibitors, and digoxin. These interactions could cause the body to metabolize the medications differently than intended and may lead to serious side effects. If drug interactions are a concern, your healthcare provider may monitor you more closely.

An Overview of PrandiMet Interactions

PrandiMet™ (repaglinide and metformin) can potentially interact with several other medications. Some of these medicines that may lead to PrandiMet drug interactions include:


    • Clarithromycin (Biaxin®)
    • Erythromycin (Ery-Tab®)
    • Isoniazid (Nydrazid®)
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Miconazole
    • Posaconazole (Noxafil®)
    • Telithromycin (Ketek®)
    • Trimethoprim (Primsol®) or trimethoprim/sulfamethoxazole (Bactrim™, Septra®)
    • Voriconazole (VFEND®)
    • Vancomycin (Vancocin®)




  • Trimethoprim or combination drugs that contain trimethoprim (Bactrim®, Bactrim® DS, Septra®, Septra® DS, Sulfatrim®).


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PrandiMet Drug Information

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