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PrandiMet Interactions

Diclofenac
Taking PrandiMet with diclofenac can increase the level of repaglinide (one of the components of PrandiMet) in your blood, increasing your risk of side effects. Your healthcare provider may need to decrease your dose of PrandiMet if you are taking these two medications together.
 
Digoxin
Theoretically, digoxin may affect the ability of the kidneys to filter metformin (one of the components of PrandiMet) from the blood, possibly leading to high levels of metformin. Your healthcare provider may need to monitor you more closely if you take these medications together.
 
Gemfibrozil
Taking PrandiMet with gemfibrozil can significantly increase the level of repaglinide (one of the components of PrandiMet) in your blood, increasing your risk of side effects. In general, these two medications should not be taken together.
 
Montelukast
Taking PrandiMet with montelukast can increase the level of repaglinide (one of the components of PrandiMet) in your blood, increasing your risk of side effects (especially dangerously low blood sugar). Your healthcare provider may need to decrease your dose of PrandiMet if you are taking these two medications together.
 
Morphine
Theoretically, morphine may affect the ability of the kidneys to filter metformin (one of the components of PrandiMet) from the blood, possibly leading to high levels of metformin. Your healthcare provider may need to monitor you more closely if you take these medications together.
 
Nefazodone
Taking PrandiMet with nefazodone can increase the level of repaglinide (one of the components of PrandiMet) in your blood, increasing your risk of side effects. Your healthcare provider may need to decrease your dose of PrandiMet if you are taking these medications together.
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PrandiMet Drug Information

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