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What Is Pioglitazone and Metformin XR Used For?

If you cannot control your type 2 diabetes through lifestyle changes alone, your healthcare provider may advise you to use pioglitazone and metformin XR. The active ingredients in the drug work together to improve insulin sensitivity and decrease the amount of sugar the liver produces. It is not approved for use in children. In some cases, it is prescribed off-label to treat polycystic ovarian syndrome.

An Overview of Uses for Pioglitazone and Metformin XR

Pioglitazone and metformin XR (Actoplus Met® XR) is a prescription medication used to treat type 2 diabetes. The drug contains a combination of different diabetes medications: pioglitazone hydrochloride (Actos®) and extended-release metformin hydrochloride. These two drugs work in different ways to help lower blood sugar.
Pioglitazone and metformin XR is a long-acting medication that is taken just once a day, in the evening. It cannot be used to treat type 1 diabetes.

Why Is Pioglitazone and Metformin XR Used for Type 2 Diabetes?

Type 2 diabetes is the most common type of diabetes (see Diabetes Types). It is also sometimes called adult-onset diabetes and noninsulin-dependent diabetes. Type 2 diabetes is a condition involving insulin resistance.
With insulin resistance, cells in the body do not respond to insulin as well as they normally should. As a result, the cells do not take sugar out of the blood very well. This is why people with type 2 diabetes have high blood sugar.
Over time, high blood sugar can lead to a number of problems, including:
(Click Diabetes Complications for more information.)
The cause of type 2 diabetes is not fully understood, although it is known that obesity and genetics play important roles. If blood sugar cannot be lowered enough through lifestyle changes (such as weight loss, diet, and exercise), a medication for type 2 diabetes, such as pioglitazone and metformin XR, may be prescribed.
7 Signs of High Blood Sugar

Pioglitazone and Metformin XR Information

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