Diabetes Channel
Topics
Medications
Quicklinks
Related Channels

Side Effects of Pioglitazone and Metformin XR

Common Side Effects

The side effect data from the prescribing information ("package insert") for pioglitazone and metformin XR was taken from clinical trials in which a combination of pioglitazone and immediate-release metformin was used. Since pioglitazone and metformin XR contains pioglitazone plus extended-release metformin, it is possible that the exact percentages might differ. Nonetheless, this data provides a general picture of the side effects that can be expected with pioglitazone and metformin XR.
 
Based on these studies, the most common side effects of pioglitazone plus immediate-release metformin included:
 
  • Upper respiratory tract infections (similar to the common cold or flu) -- in up to 13.5 percent of people
  • Swelling or fluid retention (edema) of the lower leg or ankles -- up to 11.3 percent
  • Weight gain -- up to 6.7 percent (see Actoplus Met XR and Weight Gain)
  • Diarrhea -- up to 5.8 percent
  • Nausea -- up to 5.8 percent
  • Urinary tract infections (UTIs), including bladder infections -- up to 5.8 percent
  • Dizziness -- up to 5.4 percent
  • Headache -- up to 5.3 percent
  • Sinus infection or irritation -- up to 5 percent.
     

Final Thoughts

You may experience some or none of the pioglitazone and metformin XR side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
 
Therefore, make sure to let your healthcare provider know if you develop any side effects while taking the drug or if something "just does not seem right." While it may not be related to pioglitazone and metformin XR, your healthcare provider will be able to diagnose and treat the problem.
 
Type 2 Diabetes: Fact or Fiction

Pioglitazone and Metformin XR Information

Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2017 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.