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Precautions and Warnings With Pioglitazone and Metformin XR

Who Should Not Take Pioglitazone and Metformin XR?

You should avoid pioglitazone and metformin XR if you:
  • Are allergic to it, to Actoplus Met, to Actos®, to metformin hydrochloride (Fortamet®, Glucophage®, Glucophage XR®, Glumetza®, or Fortamet®), or to any of the inactive components in the medicine. Your healthcare provider or pharmacist has a list of the inactive ingredients.
  • Have kidney disease, including kidney failure (renal failure).
  • Have metabolic or diabetic ketoacidosis (a life-threatening condition that may occur with uncontrolled diabetes). This condition needs to be treated with insulin.
  • Are seriously dehydrated.
  • Are going to have an x-ray procedure with injection of dyes (contrast agents).
  • Are going to have surgery.
  • Develop a serious condition, such as heart attack, severe infection, or a stroke.
  • Are 80 years old or older and you have not had your kidney function tested.
  • Have severe heart failure.

Final Thoughts

There are a number of situations in which pioglitazone and metformin XR should not be taken, as well as several safety concerns people should be aware of before starting treatment. However, it is possible that not all of these issues were discussed in this article. Therefore, you should talk with your healthcare provider about any warnings or precautions with pioglitazone and metformin XR that may apply to you.
Diabetes Tips for Seniors

Pioglitazone and Metformin XR Information

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