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Onglyza Uses

How Does Onglyza Work?

Onglyza is part of a class of diabetes medication called dipeptidyl peptidase-4 (DPP-4) inhibitors. DPP-4 is an enzyme that breaks down incretin hormones.
As a DPP-4 inhibitor, Onglyza slows down the breakdown of incretin hormones, increasing the level of these hormones in the body. It is this increase in incretin hormones that is responsible for the beneficial actions of Onglyza, including increasing insulin production in response to meals and decreasing the amount of glucose (sugar) that the liver produces.
Because incretin hormones are more active in response to higher blood sugar levels (and are less active in response to low blood sugar), the risk of dangerously low blood sugar (hypoglycemia) is low with Onglyza.

Can Children Use It?

Onglyza is not approved for use in children. Talk with your child's healthcare provider about the benefits and risks of using Onglyza in children.

Off-Label Uses for Onglyza

On occasion, your healthcare provider may recommend Onglyza for something other than the treatment of type 2 diabetes. Using it in combination with insulin would be an off-label use of the medication.
Diabetes Tips for Seniors

Onglyza Medication Information

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