Onglyza Drug Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when Onglyza is combined with any of the drugs listed above.
Certain Antibiotics or Antifungals
Some antibiotics and antifungals may increase the level of Onglyza in the bloodstream. As a result, a lower Onglyza dosage (2.5 mg daily) is usually recommended for people taking such medications. Check with your healthcare provider before combining Onglyza with such antibiotics or antifungals.
Certain Protease Inhibitors
Some protease inhibitors may increase the level of Onglyza in the bloodstream. In most cases, a lower dosage of Onglyza (2.5 mg daily) is recommended for use in combination with such protease inhibitors. Be sure to check with your healthcare provider before combining the diabetes medication with a protease inhibitor.
Because nefazodone may increase the level of Onglyza in the bloodstream, a lower Onglyza dose (2.5 mg daily) is usually recommended. Check with your healthcare provider before taking the diabetes drug and nefazodone together.
Onglyza may increase the risk of low blood sugar due to sulfonylurea diabetes medications. Your healthcare provider may need to lower the dosage of your sulfonylurea.