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Side Effects of NPH Insulin

Other Possible NPH Insulin Side Effects

Because NPH insulin is a non-prescription medication, little information is available about its possible side effects. Detailed side effect data is provided for prescription medications, but such data is not given for non-prescription medications. However, vague information is available and suggests that possible side effects of NPH insulin include:
  • Skin thickening or pitting at the site of the injection
  • A skin reaction (such as redness, pain, or swelling) at the site of the injection
  • High blood sugar levels (hyperglycemia) if too little is taken
  • Low blood sugar levels (hypoglycemia) if too much is taken.
Make sure those around you know how to recognize your particular signs of low blood sugar, since you may be too confused (due to low blood sugar) to recognize and adequately respond to low blood sugar. Different people may have different signs of low blood sugar.

Final Thoughts on Side Effects of NPH Insulin

You may experience some or none of the NPH insulin side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have side effects from a medicine that you have never tried. Therefore, make sure to let your healthcare provider know if you develop any side effects while taking the drug or if something "just does not seem right." While it may not be a side effect of NPH insulin, your healthcare provider will be able to diagnose and treat the problem.
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