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NovoLog Mix 50/50 Warnings and Precautions

Before you start using NovoLog Mix 50/50, warnings and precautions for the drug should be reviewed with your healthcare provider to help ensure safe treatment. It is important to know exactly how to inject the insulin, as well as what side effects may occur with treatment. You should not use NovoLog Mix 50/50 if you are allergic to any components used to make the medication.

What Should I Tell My Healthcare Provider Before Taking NovoLog Mix 50/50?

Talk with your healthcare provider prior to taking NovoLog® Mix 50/50 (insulin aspart protamine/insulin aspart) if you have:
 
  • Kidney disease, such as kidney failure (renal failure)
  • Liver disease, such as cirrhosis, liver failure, or hepatitis
  • Any allergies, including allergies to foods, dyes, or preservatives.
     
Also, let your healthcare provider know if you are:
 
  • Breastfeeding
  • Pregnant or thinking of becoming pregnant.
     
Make sure to tell your healthcare provider about any medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 

Specific Precautions and Warnings

Warnings and precautions to be aware of prior to taking NovoLog Mix 50/50 include the following:
 
  • Low blood sugar (hypoglycemia) is the most common (and usually most serious) side effect of insulin medications, including NovoLog Mix 50/50. Make sure you and those around you know how to identify the warning signs for low blood sugar and how to respond. You must test your blood sugar levels regularly while taking NovoLog Mix 50/50 or any other insulin. Low blood sugar levels can be a life-threatening problem.
     
  • NovoLog Mix 50/50 starts working quickly. Once you inject a dose of NovoLog Mix 50/50, you must start eating a meal or snack within 15 minutes, in order to avoid dangerously low blood sugar.
     
  • Liver and kidney problems may affect your NovoLog Mix 50/50 dosage. Also, changes in diet or exercise, illness, or stress may affect your blood sugar levels in such a way that your dosage needs to be adjusted.
     
  • Make sure your healthcare provider shows you exactly how to inject NovoLog Mix 50/50, how to store the drug, and how to dispose of your used needles.
     
  • NovoLog Mix 50/50 cannot be used in pumps, injected into a muscle, or used in an IV. Also, do not mix NovoLog Mix 50/50 together with any other type of insulin in the same syringe.
     
  • This diabetes medication can potentially interact with several other medications (see NovoLog Mix 50/50 Drug Interactions).
     
  • NovoLog Mix 50/50 is considered a pregnancy Category C medication. This means it may not be safe for use during pregnancy, although the full risks are not known (see NovoLog Mix 50/50 and Pregnancy).
     
  • It is not known if NovoLog Mix 50/50 passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see NovoLog Mix 50/50 and Breastfeeding).
     
Healthy Eating for People With Diabetes

NovoLog Mix 50/50 Insulin

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