Micronized Glyburide

Micronized glyburide treats type 2 diabetes by increasing insulin production in the pancreas and helping the body respond better to insulin. The medication comes in tablet form, and is usually taken once or twice a day. Micronized glyburide contains very small particles of the medication, which are better absorbed into the body. Potential side effects include stomach problems, low blood sugar, and allergic skin reactions.

 

What Is Micronized Glyburide?

Micronized glyburide (Glynase®) is a prescription medication that is used to treat type 2 diabetes (also known as non-insulin-dependent diabetes or adult-onset diabetes).
 
(Click Glyburide Uses for more information, including possible off-label uses.)
 

Who Makes Micronized Glyburide?

Brand-name micronized glyburide (Glynase) is made by Pfizer. Generic micronized glyburide is made by several manufacturers.
 

How Does Micronized Glyburide Work?

Micronized glyburide is part of a class of diabetes medications known as sulfonylureas. A sulfonylurea, such as micronized glyburide, helps the pancreas make more insulin. They may also help the body respond better to insulin. This helps to lower blood sugar and keep it under better control.
 

When and How to Take Micronized Glyburide

General considerations for when and how to take micronized glyburide include the following:
 
 
  • The drug comes in tablet form. It should be taken by mouth, usually once or twice a day.
  • When taking micronized glyburide once daily, it should be taken with breakfast (or the first main meal).
  • When taking the medication twice daily, the first dose should be taken with breakfast (or the first main meal).
  • Micronized glyburide should be taken at the same time(s) each day to maintain an even level in your blood.
  • For the drug to work properly, it must be taken as prescribed. Micronized glyburide will not work if you stop taking it.
     
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;