Incretin Mimetics
There is one incretin mimetic available, called
exenatide (
Byetta®). It works by acting like the incretin hormone in the body, increasing
insulin production and slowing digestion.
Amylin Analogues
There is one amylin analogue available, called
pramlintide (
Symlin®). This medication works like the amylin hormone in the body, increasing insulin production, slowing digestion, decreasing the production of glucose by the liver, and reducing appetite.
A Summary of Alternatives to Metformin
There are several alternatives to
metformin for
type 2 diabetes, including lifestyle changes or other medications for
diabetes. If metformin is not working for you or if it is causing bothersome side effects, ask your healthcare provider about trying an alternative to metformin.