Metanx and Pregnancy
It is not known if taking Metanx during pregnancy is safe. Because this prescription vitamin is considered a medical food, rather than a prescription medication, it doesn't have to undergo various tests to receive FDA approval. It is known that the vitamins found in Metanx do pass to the fetus, and high doses of these supplements may not be safe for a developing baby.
Metanx® is a combination vitamin used to supplement the diet in people with symptoms of diabetic peripheral neuropathy or people with abnormally high levels of homocysteine in the blood. Based on the results of animal studies, this medication is probably safe for use in pregnancy, although the full risks are currently unknown.
No research has been done to see if Metanx is safe for use during pregnancy. The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. However, Metanx is a medical food. Medical foods do not require FDA approval, and are not assigned a pregnancy category.
Metanx contains active forms of folic acid, vitamin B6, and vitamin B12. As with most vitamins, the recommended dietary allowance (RDA) of these vitamins is higher for pregnant women than for most other women of childbearing age. However, the equivalent doses of the vitamins found in Metanx are much higher than the RDA for pregnant women.
Folic acid, vitamin B6, and vitamin B12 are all passed to the developing fetus during pregnancy. In fact, the levels of these vitamins in the newborn are higher than those found in the mother. While this is not normally a cause for concern, there is not enough information to say with certainty that high doses of these vitamins are safe for use during pregnancy. Additionally, there is some concern that taking very high doses of vitamin B6 during pregnancy could cause seizures in the newborn.