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Metaglip Warnings and Precautions

Metaglip warnings and precautions include an increased risk of death due to heart or blood vessel problems, the potential for lactic acidosis, and the danger of taking the drug when pregnant. Prior to taking Metaglip, talk to your healthcare provider if you have kidney problems, congestive heart failure, or adrenal insufficiency. Metaglip warnings and precautions also extend to people with kidney disease, who are seriously dehydrated, or are going to have surgery.

Metaglip: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Metaglip® (glipizide and metformin) if you have:
  • Congestive heart failure (CHF)
  • Adrenal insufficiency or pituitary insufficiency
  • Kidney problems, including kidney failure (renal failure)
  • Liver problems, including liver failure or cirrhosis
  • Low vitamin B12 levels (pernicious anemia)
  • A history of heart attack or stroke
  • Adrenal insufficiency or adrenal fatigue
  • Pituitary gland problems
  • An upcoming surgery or procedure (including x-rays and other radiology procedures)
  • Any allergies, including allergies to sulfa drugs, food, dyes, or preservatives.
Also let your healthcare provider know if you:
  • Are pregnant or thinking of becoming pregnant
  • Are breastfeeding
  • Drink alcohol.
Make sure to tell your healthcare provider about all of the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
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