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Metaglip Drug Interactions

Metaglip Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Metaglip is taken with any of the drugs listed above.
 
Beta Blockers
Taking Metaglip with beta blockers can increase your risk of low blood sugar (hypoglycemia). As a result, you may need to be monitored more closely, and your healthcare provider may need to adjust your Metaglip dose, especially when starting or stopping a beta blocker.
 
Calcium Channel Blockers
Taking Metaglip and calcium channel blockers together can make Metaglip less effective, possibly increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your Metaglip dose, especially when starting or stopping a calcium channel blocker.
 
Certain Decongestants
If Metaglip and certain decongestants are combined, this can make Metaglip less effective, potentially increasing your chance of high blood sugar (hyperglycemia). Decongestants are in many cough and cold products, so talk to your healthcare provider before taking any cough or cold products.
 
Cimetidine
If Metaglip and cimetidine are taken together, this can increase the level of Metaglip in your blood, possibly increasing your risk of side effects. Your healthcare provider may need to adjust your dose of these medications or may suggest an alternative to cimetidine, depending on your particular situation.
 
Colesevelam
Colesevelam interferes with the absorption of Metaglip into the body, perhaps making it less effective. To avoid this interaction, be sure to take Metaglip at least four hours before colesevelam.
 
Corticosteroids
Taking Metaglip with corticosteroids can make Metaglip less effective, which may increase your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your Metaglip dose, especially when starting or stopping a corticosteroid, to prevent this interaction from occurring.
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