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Metaglip Dosage

Your specific Metaglip dosage will depend on how well your diabetes is controlled, other medical conditions you may have, and other medications you are taking. Generally, the recommended starting dose for people who have never taken metformin or glipizide is 2.5 mg/250 mg, taken once daily with a meal. This Metaglip dosage may be slowly increased, if necessary, up to a maximum dose of 20 mg/2000 mg per day.

Metaglip Dosage: An Introduction

Metaglip® (glipizide and metformin) is a combination of two different diabetes drugs: glipizide (Glucotrol® or Glucotrol XL®) and metformin hydrochloride (Fortamet®, Glucophage®, Glucophage XR®, Glumetza®, or Riomet®). The dose of Metaglip that your healthcare provider prescribes will vary, depending on a number of factors, including:
  • How well your diabetes is controlled
  • Other medical conditions you may have
  • Other medications you are currently taking.
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.

Metaglip Dosage for People New to Metformin or Glipizide

If you are not taking either metformin (Fortamet, Glucophage, Glucophage XR, Glumetza, or Riomet) or glipizide (Glucotrol or Glucotrol XL), the recommended starting dose is Metaglip 2.5 mg/250 mg, taken once daily with a meal. If your diabetes is poorly controlled (if your fasting blood sugar level is greater than 280 mg/dL), the recommended starting dose may be as high as Metaglip 2.5 mg/250 mg, taken twice daily with meals. Your healthcare provider may slowly increase your dose, if necessary, up to a total of Metaglip 20 mg/2000 mg per day.
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