Diabetes Home > Victoza Drug Interactions

Taking Victoza with insulin or oral medications that increase insulin production (such as meglitinides or sulfonylureas) can put you at risk for dangerously low blood sugar. Therefore, your doctor may choose to lower your dosage of the other drug when starting you on Victoza. Telling your doctor about all your current medications will help ensure your safety and reduce your risk of interactions with Victoza.

An Overview of Interactions With Victoza

Victoza® (liraglutide) could potentially interact with other drugs, at least in a theoretical manner. For example, Victoza could decrease the absorption of other medications, and some medications may increase the risk of low blood sugar when combined with Victoza.

Victoza and Drug Absorption

Victoza is a prescription diabetes medication that works, in part, by slowing the movement of food through the stomach. While this action is helpful for controlling blood sugar, it could possibly decrease the absorption of other medications, since most medications are much better absorbed from the small intestine, not the stomach. For most drugs, this is not likely to be a problem. However, this interaction could be a problem for any medication that is sensitive to small changes.
For instance, Victoza could decrease the absorption of warfarin (Coumadin®, Jantoven®), an anticoagulant "blood thinner" medication. However, such interactions are still largely theoretical, and studies have not shown Victoza to decrease the absorption of other drugs to any clinically significant degree.
In any case, it is a good idea to have a discussion with your healthcare provider or pharmacist about possible drug interactions before starting Victoza (or before starting any other medications, if you are already taking Victoza). He or she can review your other medications to see if any of them may be particularly sensitive to any small changes. If you happen to be taking such medications, you may need to be monitored a little more frequently than usual.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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