Diabetes Home > Symlin Uses

Symlin uses include lowering blood sugar levels after meals, decreasing the amount of sugar the liver produces, and decreasing appetite. As a result, the drug can reduce the chances of developing problems associated with high blood sugar, such as heart disease and kidney failure. Symlin should be used in conjunction with insulin and is not a substitute for it. At this time, there are no universally accepted off-label Symlin uses.

Symlin Uses: An Overview

Symlin® (pramlintide acetate) is an injectable prescription medication licensed to treat type 1 or type 2 diabetes. It is intended to be used along with insulin and is not a substitute for it. The medication should be used only in people who do not have adequate control over blood sugar using insulin.

Symlin Uses and Amylin

Symlin works to replace the actions of amylin, a hormone that is too low in many people with type 1 or type 2 diabetes. When the pancreas becomes damaged (as a result of diabetes), it can no longer produce enough amylin. Symlin works like amylin in the body, causing the following effects:
  • It slows down the emptying of food from the stomach (which slows down the increase in blood sugar after meals)
  • It decreases the amount of glucose (sugar) that the liver produces
  • It works in the brain to help people feel fuller sooner, resulting in a decrease in appetite and food intake.

Symlin Uses for Type 1 Diabetes

Type 1 diabetes usually begins in young children and teenagers. People with this type of diabetes have a pancreas that doesn't produce enough insulin -- or stops producing it altogether. This means that they need to have insulin on a regular basis to help keep their blood sugar at the right level.
Diabetes research scientists have discovered that the same cells that produce insulin also make amylin, a hormone that helps control blood sugar. Due to the damage in the pancreas, people with type 1 diabetes do not produce enough amylin.
Taking Symlin to replace the actions of amylin helps to decrease blood sugar levels after meals (known medically as postprandial blood glucose levels). This can help people with type 1 diabetes to lower their blood sugar and decrease the amount of insulin they need to take.
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Last reviewed by: Kristi Monson, PharmD;
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