Diabetes Home > Prandin Drug Interactions

Prandin drug interactions with other medications, such as beta blockers, calcium channel blockers, and NSAIDs, can cause the body to metabolize the medications differently than intended and may lead to problems. For example, these interactions may increase your risk of low blood sugar or increase the level of Prandin in your blood. If Prandin drug interactions are a concern, your healthcare provider may adjust your dosages.

An Overview of Prandin Drug Interactions

Prandin® (repaglinide) can interact with many medicines. Some of the medicines that may lead to potentially dangerous Prandin drug interactions include but are not limited to:
  • Certain antibiotics or antifungals, including:


  • Probenecid (Benuryl®, ColBenemid®)
  • Protease inhibitors, such as:
  • Salicylates, such as:
    • Salsalate (Salflex®, Disalcid®, Amigesic®)
  • Sulfonamides ("sulfa drugs"), including:
    • Sulfadiazine
    • Sulfadoxine (Fansidar®)
    • Sulfamethoxazole (Bactrim®, Septra®)
    • Sulfisoxazole (Gantrisin®)


  • Trimethoprim or combination drugs that contain trimethoprim (Bactrim®, Bactrim® DS, Septra®, Septra® DS, Sulfatrim®).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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