Diabetes Home > Pioglitazone and Metformin XR
The U.S. Food and Drug Administration has approved the prescription drug pioglitazone and metformin XR for the treatment of type 2 diabetes. The medication, which comes in tablet form, is typically taken once a day with the evening meal. Many people find it effective for managing their diabetes; however, side effects are possible, such as signs of the common cold, nausea, and diarrhea.
What Is Pioglitazone and Metformin XR?Pioglitazone and metformin XR (Actoplus Met® XR) is a prescription medication used to treat type 2 diabetes (also known as noninsulin-dependent diabetes and adult-onset diabetes). As the name implies, it contains two different diabetes medications: pioglitazone hydrochloride (Actos®) and extended-release metformin hydrochloride.
Are There Side Effects?As with any medicine, side effects are possible with pioglitazone and metformin XR. However, not everyone who takes the drug will experience problems. In fact, most people tolerate it quite well.
- Upper respiratory tract infections (similar to the common cold or flu)
- Swelling or water retention (edema) of the lower leg or ankle
- Weight gain (see Actoplus Met XR and Weight Gain)
- Urinary tract infection (UTI).