Metformin (
Glucophage®) is a prescription medication that is licensed to treat
type 2 diabetes (also known as noninsulin-dependent
diabetes or adult-onset diabetes). Metformin also comes in:
Generic metformin is made by numerous manufacturers. Glucophage and Glucophage XR are manufactured by Bristol-Myers Squibb.
Metformin is part of a class of
diabetes medications known as biguanide medications. The drug works in several ways. For example, it decreases the amount of sugar (glucose) made by the liver. It can also decrease the amount of sugar absorbed into the body (from the diet) and can make
insulin receptors more sensitive, helping the body respond better to its own insulin. All of these effects cause a decrease in blood sugar levels.
Because the medication does not increase the amount of insulin produced by the body, it is less likely to cause dangerously low blood sugar (hypoglycemia), as many other diabetes medications can do
(see Alternatives to Metformin).