Diabetes Home > Metanx Uses

How Does Metanx Work?

Metanx contains the active forms of folic acid, vitamin B6, and vitamin B12. These vitamins may help improve blood flow in damaged blood vessels, which can help damaged nerves to function properly.
Although the exact way it works is unknown, one of the ways Metanx is thought to work is by increasing nitric oxide, a natural body substance that dilates, or widens, blood vessels. When blood vessels are dilated, nutrients and oxygen, which are needed for nerve function, can flow more freely to the nerves.
Metanx also works by decreasing blood levels of homocysteine. Homocysteine is an amino acid produced by the body. High homocysteine levels (or hyperhomocysteinemia) may reduce blood flow to nerves and outer blood vessels, further increasing the risk for peripheral neuropathy, foot ulcers, and other complications of diabetes. The vitamins in Metanx help the body break down homocysteine, which can help reduce homocysteine levels.

Can Children Use Metanx?

This product is not recommended for use in children. It contains high doses of vitamins, which may not be safe for children. Do not give this product to a child without a healthcare provider's supervision.

Is It Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend this vitamin for treating something other than the conditions listed in this article. This would be known as an "off-label" use. Some off-label uses for Metanx may include the treatment of certain types of anemia.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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