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Jentadueto Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Jentadueto is combined with any of the drugs listed above.
 
Calcium Channel Blockers
Taking Jentadueto with calcium channel blockers can make Jentadueto less effective, increasing your risk for high blood sugar levels (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your Jentadueto dosage, especially when starting or stopping a calcium channel blocker.
 
Certain Decongestants
Taking Jentadueto with certain decongestants can make Jentadueto less effective, increasing your risk for high blood sugar levels (hyperglycemia). Decongestants are in many cough and cold products, so talk to your healthcare provider before taking any cough or cold products.
 
Cimetidine
Taking Jentadueto with cimetidine can increase the level of Jentadueto in your blood, increasing your risk for side effects. Your healthcare provider may need to adjust your dose of these medications, or may suggest an alternative to cimetidine.
 
Corticosteroids
Taking Jentadueto with corticosteroids can make Jentadueto less effective, increasing your risk for high blood sugar levels (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your Jentadueto dose, especially when starting or stopping a corticosteroid.
 
CYP 3A4 Inducers
The liver breaks down Jentadueto using enzymes known as CYP 3A4 enzymes. Medications known as CYP 3A4 inducers can increase the activity of these enzymes. Thus, combining Jentadueto with one of these drugs may decrease the level of Jentadueto in your body, potentially making it less effective.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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