Diabetes Home > Humulin R Warnings and Precautions
To ensure the safe use of Humulin R, warnings and precautions for the insulin should be discussed with your healthcare provider before treatment begins. Make sure he or she shows you how to inject Humulin R, how to store the drug, and how to dispose of your used needles. You should not use Humulin R if you are allergic to any components of the medication.
- Kidney disease, such as kidney failure (renal failure)
- Liver disease, such as liver failure, cirrhosis, or hepatitis
- Any allergies, including allergies to foods, dyes, or preservatives.
- Pregnant or thinking of becoming pregnant
- U-500 Humulin R is five times as concentrated as standard U-100 Humulin R. Use extreme caution when using this concentrated form of insulin, as small inaccuracies in dosing can easily lead to overdoses (or underdoses).
- Low blood sugar (hypoglycemia) is the most common (and usually most serious) side effect of insulin medications, including Humulin R. Make sure you and those around you know how to identify the warning signs for low blood sugar and how to respond. You must test your blood sugar levels regularly while taking Humulin R or any other insulin. Low blood sugar levels can be a life-threatening problem.
- Liver and kidney problems may affect your Humulin R dosage. Also, changes in diet or exercise, illness, or stress may affect your blood sugar levels in such a way that your dosage needs to be adjusted.
- Make sure your healthcare provider shows you exactly how to inject Humulin R, how to store the drug, and how to dispose of your used needles.
- Even though Humulin R is available without a prescription, it should only be used with your healthcare provider's approval and supervision. Using this medication inappropriately can be lethal.
- This diabetes medication can potentially interact with several other medications (see Humulin R Drug Interactions).
- Humulin R is considered a pregnancy Category B medication. This means it is most likely safe for use during pregnancy, although the full risks are not known (see Humulin R and Pregnancy).
- It is not known if Humulin R passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Humulin R and Breastfeeding).