Humalog Mix50/50 is a prescription diabetes medication. It contains a rapid-acting insulin and an intermediate-acting insulin, and is used to control blood sugar in people with type 1 or type 2 diabetes. Humalog Mix50/50 comes in injectable form and is injected just under the skin immediately before meals, within 15 minutes before you start eating. Potential side effects include allergic reactions and hypoglycemia.
Humalog Mix50/50 is manufactured by Eli Lilly and Company.
How Does Humalog Mix50/50 Work?
Humalog Mix50/50 contains two different insulins: one that is rapid-acting (insulin lispro) and one that is intermediate-acting (insulin lispro protamine). It starts working quickly and continues to work for several hours. Ideally, using Humalog Mix50/50 decreases the number of injections per day, since it combines two types of insulin into one injection.
Insulin is a hormone that is naturally produced by the pancreas. This hormone is important for several functions, such as controlling blood sugar. Insulin helps the cells of your body remove glucose ("sugar") from your bloodstream. This sugar fuels your body's cells, giving them the energy they need to work properly. You may need to take insulin if your pancreas has trouble making enough, which is the case in people with type 1 diabetes and in some people who have type 2 diabetes.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Humalog Mix50/50 [package insert]. Indianapolis, IN: Lily USA, LLC;2013 March.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: Approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed September 12, 2008.
Eli Lilly and Company, Important information regarding the upcoming discontinuation and current supply of the original Prefilled Pen containing the Humalog brand of insulin (8/2010). e-Pharm/alert Web site. Available at: http://whatcounts.jobson.com/dm?id=BB7B0E5EB0637621C657BB7B5A08BC0B. Accessed August 16, 2010.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 7th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2005.
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