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Rare Glyburide Side Effects

Rare glyburide side effects occur in 1 percent or fewer of people taking the medication. Because these side effects are so uncommon, it is difficult to tell whether they are due to the medication or something else.
Some of these rare side effects include but are not limited to:
  • Anemia
  • Hepatitis
  • Low sodium in the blood (hyponatremia)
  • Blurred vision
  • Reaction with alcohol, causing stomach upset, vomiting, shakiness, sweating, and stomach cramps.
Oral diabetes drugs, including glyburide, may increase the risk of death due to heart or blood vessel problems when compared to diabetes treatment with diet or insulin. This warning is based on one research study that looked at a diabetes medication similar to glyburide. However, it is unclear at this time how serious this risk may be in people taking glyburide.

Glyburide Side Effects: Final Thoughts

You may experience some or none of the glyburide side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have side effects from a medicine that you have never tried. Therefore, be sure to let your healthcare provider know if you develop any side effects while taking the drug. Also, let your healthcare provider know if you develop something that "just does not seem right." While it may not be a side effect of glyburide, your healthcare provider will be able to diagnose and treat the problem.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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