In clinical studies, this combination product lowered HbA1c (hemoglobin A1c) levels and fasting blood sugar levels more than when each of the active ingredients in the drug was used alone. By controlling blood sugar levels, Janumet XR can help reduce the risk of developing long-term problems related to diabetes, such as heart, nerve, eye, or kidney problems.
While most people tolerate this medicine well, it is not suitable for some people. Before starting treatment with Janumet XR, your healthcare provider will need information on all other medications you are taking and will examine your medical history. People who have liver, heart, or kidney problems may not be able to safely use this drug.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed March 25, 2013.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
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