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Research Findings on Omega-3 Fatty Acids
Randomized clinical trials have found that omega-3 supplementation reduces the incidence of cardiovascular disease and events, such as heart attack and stroke, and slows down the progression of atherosclerosis (hardening of the arteries). However, these studies were not done in populations that were at higher risk, such as those with type 2 diabetes.
There is somewhat more literature available on omega-3 supplementation as a possible remedy for diabetes than for most other alternative treatments for this condition. The Cochrane Collaboration published a 2001 analysis of 18 randomized placebo-controlled trials on fish oil supplementation in type 2 diabetes. The authors found that fish oil lowered triglycerides and raised LDL cholesterol, but had no significant effect on fasting blood glucose, HbA1c, total cholesterol, or HDL cholesterol. (The authors did not identify and include studies with cardiovascular outcomes, but noted that this is an area for further research.)
In 2004, another analysis was published by the Agency for Healthcare Research and Quality of 18 studies on omega-3 fatty acids for a number of measurable outcomes in type 2 diabetes. This study confirmed virtually all the Cochrane authors' findings, except for finding no significant effect on LDL cholesterol.