Available by prescription only, Bydureon is a drug licensed for the treatment of type 2 diabetes. It has several effects on the body, including increasing insulin production after meals and decreasing the amount of glucose that the liver produces. The medication comes as an injection that is given just beneath the skin once a week. Side effects may include nausea, constipation, or diarrhea.
Bydureon belongs to a small group of medications known as incretin mimetics. These drugs mimic the actions of incretin hormones in the body. As an incretin mimetic, Bydureon increases insulin production in response to meals and decreases the amount of glucose (sugar) produced by the liver. This drug also slows down the emptying of food from the stomach, an effect that usually decreases the amount of food that people eat.
Bydureon is also known as a glucagon-like peptide-1 (GLP-1) receptor agonist. GLP-1 is the specific type of incretin hormone that Bydureon mimics. It is an "agonist" because it binds to and activates GLP-1 receptors in the body.
Because incretin hormones are more active in response to higher blood sugar levels and are less active in response to low blood sugar levels, the risk of dangerously low blood sugar (hypoglycemia) is minimal with Bydureon. However, combining it with other diabetes medications to lower blood sugar levels can increase the risk for hypoglycemia (see Bydureon and Blood Sugar).
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Bydureon [package insert]. San Diego, CA: Amylin Pharmaceuticals, Inc.;2012 January.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed March 16, 2012.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind.
Site users seeking medical advice about their specific situation should consult with their own physician. Click