Diabetes Home > Amaryl Side Effects

Although most people have no problems with Amaryl, side effects are possible, such as low blood sugar, dizziness, and weakness. In many cases, such problems are mild and are treated easily or require no treatment. However, there are several side effects that you should report immediately to your healthcare provider, including shortness of breath, cold sweats, and chest pain.

An Introduction to Amaryl Side Effects

As with any medicine, side effects are possible with Amaryl® (glimepiride). However, not everyone who takes it will experience problems. In fact, most people tolerate the drug well. If side effects do occur, in most cases, they are minor, meaning they require no treatment or are treated easily by you or your healthcare provider. Serious reactions are less common.
(This article discusses most, but not all, side effects seen with Amaryl. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects of Amaryl

Amaryl has been studied thoroughly in clinical trials, with many people having been evaluated. In these studies, side effects that occurred in a group of people taking the drug are always documented and compared to those that occurred in a similar group of people not taking the medicine.
Thus, it is possible to see what side effects occurred, how often they appeared, and how they compared to the group not taking the medicine. Based on these studies, the most common Amaryl side effects include:
  • Low blood sugar (hypoglycemia) -- occurring in up to 1.7 percent of people (see Amaryl and Blood Sugar)
  • Dizziness -- up to 1.7 percent
  • Weakness -- up to 1.6 percent
  • Headache -- up to 1.5 percent
  • Upset stomach (nausea) -- up to 1.1 percent.
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Last reviewed by: Kristi Monson, PharmD;
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