Diabetes Home > Amaryl Alternatives

Some alternatives to Amaryl for treating type 2 diabetes include lifestyle changes, other oral diabetes medications, and insulin. For many people, lifestyle changes, such as more physical activity and changes in diet, may not be enough to adequately control diabetes. In this case, other medications, including oral and injectable medications, may be necessary.

Amaryl Alternatives Explained

Amaryl® (glimepiride) is a prescription medication used for the treatment of type 2 diabetes. For most people, Amaryl is effective in treating their diabetes. In addition, most people tolerate the medication well. However, as with all medicines, side effects can occur. Or, in some people, the medicine may not completely control their diabetes. Fortunately, there are several alternatives to Amaryl.
Some of these Amaryl alternatives include:

Oral Diabetes Medicines as Alternatives to Amaryl

Fortunately, there are many other different types of oral medications available to treat type 2 diabetes, including:
  • Sulfonylureas
  • Biguanides
  • Meglitinides
  • Thiazolidinediones
  • Alpha-glucosidase inhibitors
  • Dipeptidyl peptidase inhibitors
  • Ergot alkaloids
  • Sodium-glucose co-transporter 2 inhibitors (SGLT2 inhibitors)
  • Bile acid sequestrants
  • Combination medications.
Sulfonylureas are medications that force the pancreas to produce more insulin. Because of this, they are very effective, but they are also more likely to cause dangerously low blood sugar (hypoglycemia). Besides Amaryl, these medications include:
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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