Diabetes Home > Actoplus Met Substitutes

Actoplus Met® (pioglitazone and metformin) is a medication licensed for the treatment of type 2 diabetes. Most people have no problems when taking it, and if any side effects do occur, they are usually mild and easily treated. However, in some cases -- whether due to bothersome (or even serious) side effects or because the drug is not working as well as hoped -- a substitute for Actoplus Met needs to be considered.
Other options for type 2 diabetes treatment include other oral diabetes medications, lifestyle changes, and insulin or other injectable diabetes drugs. The specific substitute your healthcare provider recommends will depend on what other medications you have tried and how well your diabetes is currently controlled, among other things.
Examples of alternative oral medicines include:
(Click Actoplus Met Alternatives for a more complete list of substitute drugs, the pros and cons of each, and the lifestyle changes that may help with treatment for type 2 diabetes.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
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