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Levemir and Pregnancy

It is generally considered safe to take Levemir (insulin detemir) during pregnancy. In human studies, the medication did not appear to increase the risk of birth defects. If you are using Levemir during pregnancy, talk to your healthcare provider about your insulin requirements, as they may change during the course of your pregnancy.

Levemir and Pregnancy: An Overview

Levemir® (insulin detemir) is a prescription diabetes medication used to treat type 1 and type 2 diabetes. It is a long-acting form of insulin. Based on the available animal and human data, the drug appears to be safe for use during pregnancy.

Levemir and Pregnancy Category B

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category B is given to medicines that have not been adequately studied in pregnant humans but do not appear to cause harm to the fetus in animal studies. Medications that have been shown to be safe for use in pregnancy in humans (but have caused problems in laboratory animals) are also given a Category B rating.
In animal studies, Levemir increased the risk of various birth defects. However, in these studies, regular human insulin also increased the risk of birth defects, and it appears that Levemir is probably as safe as regular human insulin -- at least in animals.
In human studies, Levemir did not appear to increase the risk of birth defects.
If you are already taking Levemir and plan to continue taking it during pregnancy, you should be aware that pregnancy usually affects your insulin requirements. You likely will need more insulin during pregnancy, especially during the last trimester. As a pregnant woman with diabetes, you will need more prenatal care than the average pregnant woman.
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