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Lantus Warnings and Precautions

You may not be able to safely take Lantus if you have certain health conditions, such as liver disease, kidney disease, or specific allergies. Therefore, it is important to review Lantus warnings and precautions with your healthcare provider prior to taking the medication. You should also tell your healthcare provider about any other medications you are taking, as Lantus can react negatively with some medications.

Lantus: What Should I Tell My Healthcare Provider?

Talk with your healthcare provider prior to taking Lantus® (insulin glargine) if you have:
  • Liver disease, such as liver failure, cirrhosis, or hepatitis
  • Kidney disease, such as kidney failure (renal failure)
  • An insulin pump
  • Any allergies, including allergies to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about any medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Lantus Warnings and Precautions

Precautions and warnings to be aware of prior to taking Lantus include the following:
  • Lantus should not be used in insulin pumps. Also, it should not be mixed with other insulins in the same syringe. Lantus should never be diluted.
  • Lantus must be given as a subcutaneous injection (just under the skin). It should never be injected into a vein, given by IV, or injected into a muscle.
  • Low blood sugar (hypoglycemia) is the most common (and usually most serious) side effect of insulin medications. Make sure you and those around you know how to identify the warning signs of low blood sugar and how to respond. You must test your blood sugar levels regularly while taking Lantus or any other insulin. Low blood sugar levels can be a life-threatening problem.
  • Any time you start, stop, or change your Lantus dosage, you may need to monitor your blood sugar more closely than usual.
  • Liver and kidney problems may affect your Lantus dosage. Also, changes in diet or exercise, illness, or stress may affect your blood sugar levels in such a way that your dosage needs to be adjusted.
  • Make sure your healthcare provider shows you exactly how to inject Lantus, how to store the drug, and how to dispose of your used needles.
  • This diabetes medication can potentially interact with several other medications (see Lantus Drug Interactions).
  • Lantus is considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are not known (see Lantus and Pregnancy).
  • It is not known if Lantus passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Lantus and Breastfeeding).
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