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Kombiglyze XR Drug Interactions

Cimetidine
Taking Kombiglyze XR with cimetidine can increase the level of Kombiglyze XR in your blood, increasing your risk of side effects. Your healthcare provider may need to adjust your dose of these medications or may suggest an alternative to cimetidine.
 
Corticosteroids
Taking Kombiglyze XR with corticosteroids can make Kombiglyze XR less effective, increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your Kombiglyze XR dose, especially when starting or stopping a corticosteroid.
 
Digoxin
Taking digoxin and Kombiglyze XR together may affect the level of both medications in your blood. Your healthcare provider should monitor the level of digoxin in your blood, especially when starting or stopping Kombiglyze XR.
 
Diuretics
Combining Kombiglyze XR with diuretics can make Kombiglyze XR less effective, increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your Kombiglyze XR dose, especially when starting or stopping a diuretic.
 
Taking Kombiglyze XR with furosemide, which is a diuretic, can affect the levels of both medications in your blood. This may increase your risk of Kombiglyze XR side effects and may make furosemide less effective. Your healthcare provider may need to adjust your doses of these medications to prevent this interaction.
 
Estrogens
Taking Kombiglyze XR with estrogens can make Kombiglyze XR less effective, increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your Kombiglyze XR dose, especially when starting or stopping an estrogen.
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Kombiglyze XR Medication Information

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