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Kazano Uses

How Does It Work?

As mentioned already, Kazano contains two diabetes medicines: alogliptin and metformin. These two medicines work in different ways to control blood sugar.
Alogliptin belongs to a group of medicines known as dipeptidyl peptidase-4 (DPP-4) inhibitors. DPP-4 is an enzyme that breaks down certain hormones known as incretin hormones. These hormones cause insulin to be released from the pancreas (which lowers blood glucose levels) in response to meals. They also reduce the amount of glucagon released by the pancreas, which reduces glucose (sugar) production by the liver.
By blocking the DPP-4 enzyme, Kazano increases the level of incretin hormones in the blood. This causes more insulin to be made in response to meals, and reduces the amount of glucose made by the liver.
Metformin belongs to a group of medicines known as biguanides. It lowers blood sugar levels in several ways, including by:
  • Decreasing the amount of glucose made by the liver
  • Decreasing the amount of sugar absorbed into the body through the small intestines
  • Improving insulin sensitivity, which helps increase glucose uptake and use by cells.

Is It Safe for Children to Use Kazano?

Kazano has not been adequately studied in children, and is not approved for use in children (usually defined as individuals younger than 18 years old). Talk to your child's healthcare provider about the risks and benefits of using this medication in children.

Can Older Adults Use It?

Yes -- older adults can use this medication. However, older adults are more likely to have reduced kidney function, which may put them at a higher risk for Kazano side effects. If you are 80 years old or older, your healthcare provider should check your kidney function before starting Kazano treatment. People with kidney disease should not be treated with this drug.
Healthy Eating for People With Diabetes

Kazano Medication Information

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