Diabetes Channel
Related Channels

Januvia Warnings and Precautions

Some Januvia warnings and precautions to be aware of are related to potential allergic reactions the drug may cause, while others concern the danger of taking the medication when you have kidney problems. Before taking Januvia, notify your healthcare provider about any kidney problems or allergies you may have. It's possible that Januvia could interact with other drugs, so tell your healthcare provider about any other medicines you are taking.

Januvia: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Januvia® (sitagliptin) if you have:
  • Kidney problems, including kidney failure (renal failure)
  • Had pancreatitis (inflammation or infection of the pancreas) in the past
  • Any allergies, including allergies to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Tell your healthcare provider about all of the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Some Januvia Warnings and Precautions

Some Januvia warnings and precautions to be aware of include the following:
  • Very preliminary data suggests incretin mimetics, such as Januvia, may increase the risk of precancerous cellular changes (called pancreatic duct metaplasia) in people with type 2 diabetes. Researchers are continuing to study the possibility that incretin mimetics might increase the risk of pancreatic cancer, although at this time there is not enough information to know for sure if there is any increased risk. 
  • There have been some reports of pancreatitis in people taking Januvia. This is probably most likely to occur shortly after the drug is first started or when the dosage is increased. Be sure to let your healthcare provider know right away if you have signs of pancreatitis, such as:
    • Nausea
    • Vomiting
    • Loss of appetite
    • Severe persistent abdominal pain that sometimes radiates to the back.
  • Januvia is considered a pregnancy Category B medication. This means that Januvia is probably safe for use in pregnant women, although the full risks of taking Januvia during pregnancy are not known. Talk to your healthcare provider before taking Januvia while pregnant (see Januvia and Pregnancy).
  • It is not known if Januvia passes through breast milk. Therefore, if you are breastfeeding or plan to start, be sure to discuss this with your healthcare provider.
  • Januvia is cleared from the body by way of the kidneys, and people with kidney problems (including people on dialysis) need to take lower doses of Januvia.
  • The risk of low blood sugar (hypoglycemia) is low for Januvia. Also, taking Januvia with metformin (Fortamet®, Glucophage®, Glucophage XR®, Glumetza®, or Riomet®), pioglitazone (Actos®), or rosiglitazone (Avandia®) usually does not increase the risk of low blood sugar.

However, Januvia has not been studied with other diabetes drugs, and it is not known if Januvia will increase the chance of hypoglycemia when taken with these medications (see Januvia and Blood Sugar for more information).  

7 Signs of High Blood Sugar

Januvia Medicine

Referring Pages:
Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2020 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.