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Januvia Dosing

For most people taking Januvia, dosing guidelines call for taking 100 mg of the drug once daily; however, your dose may be lower if you have kidney problems. Other factors that may affect the amount that your doctor recommends include such things as how well your diabetes is controlled and other medical conditions you may have.

An Introduction to Dosing With Januvia

The dose of Januvia® (sitagliptin) your healthcare provider prescribes will vary, depending on a number of factors, including:
  • How well your diabetes is controlled
  • Other medical conditions you may have
  • Other medications you may be taking.
As is always the case, do not adjust your dose unless your healthcare provider specifically tells you to do so.

Januvia Dosage for Type 2 Diabetes

For most people, the Januvia dose for type 2 diabetes is 100 mg once daily. However, because this medication is cleared from the body by the kidneys, people with kidney problems will need lower doses. Before you start treatment with Januvia, your healthcare provider should check your kidney function, using a simple blood test.

General Information on Taking Januvia

Some considerations to keep in mind during treatment with Januvia include the following:
  • Januvia comes in tablet form. It should be taken by mouth once a day.
  • You may take a dose with or without food. If Januvia bothers your stomach, try taking it with food.
  • The tablets may be broken or crushed if necessary. 


  • Take Januvia at the same time each day. This will help to maintain an even level of the diabetes medication in your blood.
  • If you do not take your Januvia as scheduled, take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and continue on your regular schedule. Do not take a double dose.
  • For this medicine to work properly, you have to take it as prescribed. Januvia will not work if you take it differently than how your healthcare provider recommends.
If you are unsure about anything related to dosing with Januvia or your specific dosage, talk to your doctor, nurse, or pharmacist. Do not stop taking this drug without first discussing it with your healthcare provider.
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