Drug Interactions With Irbesartan

When various medications are taken together, there is a possibility of developing negative drug interactions. With irbesartan, these interactions may occur if it is taken with medicines such as potassium supplements, diuretics, or potassium-sparing diuretics. Drug interactions with irbesartan can cause your body to metabolize the medications differently than intended or lead to side effects, such as extreme low blood pressure or excessive levels of potassium in your blood.

Drug Interactions With Irbesartan: An Overview

Irbesartan (Avapro®) can potentially interact with a number of other medicines. Some of these drug interactions with irbesartan can include:
 

More Detail on Interactions With Irbesartan

The following sections explain in detail how various drugs can interact negatively with irbesartan if taken together.
 
 
Diuretics
When taking irbesartan with a diuretic, your blood pressure may decrease too much. This is more likely to occur when irbesartan is first started. In order to decrease the chances of this interaction, your healthcare provider may change the dosages of either medicine, start you on a lower dose of irbesartan, and/or monitor you more closely.
 
Potassium Supplements
If you are taking a potassium supplement with irbesartan, the levels of potassium in your blood may become too high. This can cause serious problems. Talk to your healthcare provider about using potassium and irbesartan together in your particular situation.

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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