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Insulin Aspart Protamine/Insulin Aspart

Insulin aspart protamine/insulin aspart is a prescription drug approved for controlling blood sugar in people with type 1 or type 2 diabetes. It contains a rapid-acting insulin and an intermediate-acting insulin. Insulin aspart protamine/insulin aspart, which is given by injection, is usually taken twice a day immediately before the morning and evening meals. Potential side effects include injection site reactions and low blood sugar levels.

What Is Insulin Aspart Protamine/Insulin Aspart?

Insulin aspart protamine/insulin aspart (NovoLog® Mix 70/30, NovoLog® Mix 50/50) is a prescription form of insulin used to treat type 1 diabetes and type 2 diabetes. It contains insulin aspart (a rapid-acting insulin) mixed with insulin aspart protamine (an intermediate-acting insulin). It is usually taken twice a day, with each dose covering two meals or a meal and a snack.
(Click What Is Insulin Aspart Protamine/Insulin Aspart Used For? for more information, including possible off-label uses.)

Insulin Aspart Protamine/Insulin Aspart Side Effects

As with any medicine, side effects are possible with insulin aspart protamine/insulin aspart. However, not everyone who uses the medication will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider. Serious side effects are less common.
Possible side effects of insulin aspart protamine/insulin aspart (as well as all other forms of insulin) include, but are not limited to:
  • Low blood sugar levels (hypoglycemia)
  • A skin reaction at the injection site
  • Thickening or pitting of the skin at the injection site.
(Click Side Effects of Insulin Aspart Protamine/Insulin Aspart to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
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