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Humulin 70/30 Drug Interactions

When you take fibrate cholesterol medications, monoamine oxidase inhibitors (MAOIs), or ACE inhibitors in combination with Humulin 70/30, drug interactions could occur. These interactions may increase the risk of low blood sugar, which can become dangerous quickly. To help minimize drug interactions, be sure to check with your healthcare provider any time you start, stop, or change the dose of any medication.

Humulin 70/30 Interactions: An Overview

Insulin medications, including Humulin® 70/30 (NPH insulin/regular insulin), can potentially interact with numerous different medications. In fact, any medication that has the potential to affect your blood sugar can also interact with Humulin 70/30. Because there are so many potential Humulin 70/30 interactions (and because some are relatively insignificant), this article does not discuss every possible interaction.
Some interactions may increase blood sugar levels, which is not healthy but is usually not immediately dangerous. Typically, most people will notice higher blood sugar (when testing) and will adjust their insulin dosage as recommended by their healthcare provider long before these interactions become dangerous. These interactions are not discussed in this article.
However, other Humulin 70/30 drug interactions can result in dangerously low blood sugar levels (known medically as hypoglycemia). These interactions can potentially be dangerous (even fatal) rather quickly, even if you check your blood sugar regularly. Some of the medicines that may cause dangerously low blood sugar when combined with Humulin 70/30 include:
  • Angiotensin-converting enzyme inhibitors ("ACE inhibitors"), such as:










    • Aspirin (Ecotrin®, Bayer®, Anacin®)
    • Choline magnesium trisalicylate (Trilisate®)
    • Diflunisal (Dolobid®)
    • Salsalate (Salflex®, Disalcid®, Amigesic®)


  • Sulfonamide antibiotics ("sulfa drugs"), such as:


    • Sulfadiazine
    • Sulfadoxine (Fansidar®)
    • Sulfamethoxazole (Bactrim®, Septra®)
    • Sulfisoxazole (Gantrisin®).


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Humulin 70/30 Insulin Information

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