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Humulin 50/50 Warnings and Precautions

You may not be able to safely use Humulin 50/50 if you have certain health conditions, such as kidney or liver disease. To avoid potentially life-threatening complications with Humulin 50/50, warnings and precautions should be fully discussed with your healthcare provider prior to using this form of insulin. Even though Humulin 50/50 is available without a prescription, you should not use this medication without the approval and supervision of your healthcare provider.

What Should I Tell My Healthcare Provider Before Taking Humulin 50/50?

Talk with your healthcare provider prior to taking Humulin® 50/50 (NPH insulin/regular insulin) if you have:
 
  • Kidney disease, such as kidney failure (also known as renal failure)
  • Liver disease, such as liver failure (hepatic failure), hepatitis, or cirrhosis
  • Any allergies, including allergies to foods, dyes, or preservatives.
     
Also, let your healthcare provider know if you are:
 
  • Breastfeeding
  • Pregnant or thinking of becoming pregnant.
     
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
As of July 2009, Eli Lilly and Company decided to stop producing Humulin 50/50 due to low product demand. It was initially estimated that current supplies of the medication may last until April 2010, but the supplies have appeared to have run out earlier than expected (as of December 2009). If you are currently taking Humulin 50/50, your healthcare provider will need to switch you to one of the other types of insulin.
 
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Humulin 50/50 Insulin Information

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