Humulin 50/50 Warnings and Precautions

You may not be able to safely use Humulin 50/50 if you have certain health conditions, such as kidney or liver disease. To avoid potentially life-threatening complications with Humulin 50/50, warnings and precautions should be fully discussed with your healthcare provider prior to using this form of insulin. Even though Humulin 50/50 is available without a prescription, you should not use this medication without the approval and supervision of your healthcare provider.

What Should I Tell My Healthcare Provider Before Taking Humulin 50/50?

Talk with your healthcare provider prior to taking Humulin® 50/50 (NPH
 insulin/regular insulin) if you have:
 
  • Kidney disease, such as kidney failure (also known as renal failure)
  • Liver disease, such as liver failure (hepatic failure), hepatitis, or cirrhosis
  • Any allergies, including allergies to foods, dyes, or preservatives.
     
Also, let your healthcare provider know if you are:
 
  • Breastfeeding
  • Pregnant or thinking of becoming pregnant.
     
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
As of July 2009, Eli Lilly and Company has decided to stop producing Humulin 50/50 due to low product demand. It is estimated that current supplies of the medication may last until April 2010. If you are currently taking Humulin 50/50, your healthcare provider will need to switch you to one of the other types of insulin.
 
(Humulin 50/50 Warnings and Precautions Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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