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Humulin 50/50 and Pregnancy

The FDA classifies Humulin 50/50 as a pregnancy Category B medication, meaning it is generally considered safe for use during pregnancy. The medication helps to control blood sugar levels, which is important for women who have diabetes or gestational diabetes. If you are using Humulin 50/50 and pregnancy occurs, you may need to adjust your dosage, as pregnancy usually affects insulin requirements.

Taking Humulin 50/50 During Pregnancy: An Overview

Humulin® 50/50 (NPH insulin/regular insulin), like many types of insulin, is generally considered safe for pregnant women. It has been around long enough for healthcare providers to have plenty of experience with the use of this medication during pregnancy.
As of July 2009, Eli Lilly and Company decided to stop producing Humulin 50/50 due to low product demand. It was initially estimated that current supplies of the medication may last until April 2010, but the supplies have appeared to have run out earlier than expected (as of December 2009). If you are currently taking Humulin 50/50, your healthcare provider will need to switch you to one of the other types of insulin.

Pregnancy Category B

The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category B is given to medicines that have not been adequately studied in pregnant humans, but do not appear to cause harm to the fetus in animal studies. Most healthcare providers are comfortable recommending pregnancy category B medications to pregnant women.
Although it was originally thought that insulin molecules are too large to cross the placenta, it is now known that some insulins, in some circumstances, may cross the placenta. In general, most healthcare providers consider Humulin 50/50 safe for use during pregnancy. It is very important for pregnant women with diabetes (including gestational diabetes) to control their blood sugar levels, and Humulin 50/50 can be useful to help keep blood sugar levels under control.
When using insulin, the most significant risk to a pregnant woman (or to anyone, for that matter) is the risk of dangerously low blood sugar levels, known medically as hypoglycemia. Make sure to check your blood sugar often, and be sure you know exactly what to do if you experience low blood sugar levels.
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