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When and How to Take Humalog

General considerations for when and how to take Humalog include the following:
  • This diabetes medication comes in injectable form. It is injected just under the skin (subcutaneously) within 15 minutes before or after a meal. Alternatively, Humalog can be used in an insulin pump. If necessary, Humalog can also be given intravenously (by IV) in a hospital or other similar healthcare setting. 
  • Your healthcare provider should show you exactly how to inject the drug. It can be injected into the skin and fat layer of the abdomen (stomach), upper arm, or thigh. Choose one of these three areas, and rotate injection sites within your chosen area.
  • Humalog comes in vials, cartridges (for use in certain pens), and KwikPen™ prefilled pens. To use the pen, you will need specific types of needles known as "pen needles." Each time you inject the drug, you need to use a new needle. To use it from the vial, you will need insulin syringes with needles. 


  • Because Humalog is a solution, not a suspension, you don't need to shake or swirl it.
  • Check with your healthcare provider before mixing Humalog with any other insulins in the same syringe. If you do mix it with other insulins, be sure to draw up Humalog into the syringe first and the other insulin second.
  • For this diabetes drug to work properly, it must be taken as prescribed. Humalog will not work if you stop taking it. Make sure to monitor your blood sugar levels as your healthcare provider recommends.

Dosing Information

The dose of Humalog your healthcare provider recommends will vary, depending on a number of factors, including:
  • The carbohydrate content of your meals
  • Your current dose of other insulins
  • How you respond to the drug (especially as measured by your blood sugar levels)
  • Other medications you are taking
  • Other medical conditions you may have.
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
(Click Humalog Dosage for more information.)
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